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AAV2-mediated transfer of the human aquaporin-1 cDNA restores fluid secretion from irradiated miniature pig parotid glands

Previously (Shan et al, 2005), we reported that adenoviral vector-mediated transfer of the human aquaporin-1 (hAQP1) cDNA to minipig parotid glands following irradiation (IRti) transiently restored salivary flow to near normal levels. This study evaluated a serotype 2, adeno-associated viral (AAV2)...

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Detalles Bibliográficos
Autores principales: Gao, Runtao, Yan, Xing, Zheng, Changyu, Goldsmith, Corinne M., Afione, Sandra, Hai, Bo, Xu, Junji, Zhou, Jian, Zhang, Chunmei, Chiorini, John A., Baum, Bruce J., Wang, Songlin
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3015016/
https://www.ncbi.nlm.nih.gov/pubmed/20882054
http://dx.doi.org/10.1038/gt.2010.128