Endothelial activation and apoptosis mediated by neutrophil-dependent interleukin 6 trans-signalling: a novel target for systemic sclerosis?

OBJECTIVES: Systemic sclerosis (SSc) is a connective tissue disease associated with significant morbidity and mortality and generally inadequate treatment. Endothelial cell activation and apoptosis are thought to be pivotal in the pathogenesis of this disease, but the mechanisms that mediate this re...

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Detalles Bibliográficos
Autores principales: Barnes, Theresa C, Spiller, David G, Anderson, Marina E, Edwards, Steven W, Moots, Robert J
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2010
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3015068/
https://www.ncbi.nlm.nih.gov/pubmed/21068092
http://dx.doi.org/10.1136/ard.2010.133587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3015068/
https://www.ncbi.nlm.nih.gov/pubmed/21068092
http://dx.doi.org/10.1136/ard.2010.133587

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