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Tau, prions and Aβ: the triad of neurodegeneration

This article highlights the features that connect prion diseases with other cerebral amyloidoses and how these relate to neurodegeneration, with focus on tau phosphorylation. It also discusses similarities between prion disease and Alzheimer’s disease: mechanisms of amyloid formation, neurotoxicity,...

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Detalles Bibliográficos
Autores principales: Reiniger, Lilla, Lukic, Ana, Linehan, Jacqueline, Rudge, Peter, Collinge, John, Mead, Simon, Brandner, Sebastian
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3015202/
https://www.ncbi.nlm.nih.gov/pubmed/20473510
http://dx.doi.org/10.1007/s00401-010-0691-0