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Effects of a defective ERAD pathway on growth and heterologous protein production in Aspergillus niger
Endoplasmic reticulum associated degradation (ERAD) is a conserved mechanism to remove misfolded proteins from the ER by targeting them to the proteasome for degradation. To assess the role of ERAD in filamentous fungi, we have examined the consequences of disrupting putative ERAD components in the...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016150/ https://www.ncbi.nlm.nih.gov/pubmed/20922374 http://dx.doi.org/10.1007/s00253-010-2916-5 |