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Effects of a defective ERAD pathway on growth and heterologous protein production in Aspergillus niger

Endoplasmic reticulum associated degradation (ERAD) is a conserved mechanism to remove misfolded proteins from the ER by targeting them to the proteasome for degradation. To assess the role of ERAD in filamentous fungi, we have examined the consequences of disrupting putative ERAD components in the...

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Detalles Bibliográficos
Autores principales:	Carvalho, Neuza D. S. P., Arentshorst, Mark, Kooistra, Rolf, Stam, Hein, Sagt, Cees M., van den Hondel, Cees A. M. J. J., Ram, Arthur F. J.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Applied Genetics and Molecular Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016150/ https://www.ncbi.nlm.nih.gov/pubmed/20922374 http://dx.doi.org/10.1007/s00253-010-2916-5

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