Physicochemical properties of pore residues predict activation gating of Ca(V)1.2: A correlation mutation analysis

Single point mutations in pore-forming S6 segments of calcium channels may transform a high-voltage-activated into a low-voltage-activated channel, and resulting disturbances in calcium entry may cause channelopathies (Hemara-Wahanui et al., Proc Natl Acad Sci U S A 102(21):7553–7558, 16). Here we a...

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Detalles Bibliográficos
Autores principales: Beyl, Stanislav, Depil, Katrin, Hohaus, Annette, Stary-Weinzinger, Anna, Timin, Eugen, Shabbir, Waheed, Kudrnac, Michaela, Hering, Steffen
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Ion Channels, Receptors and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016219/
https://www.ncbi.nlm.nih.gov/pubmed/20924598
http://dx.doi.org/10.1007/s00424-010-0885-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016219/
https://www.ncbi.nlm.nih.gov/pubmed/20924598
http://dx.doi.org/10.1007/s00424-010-0885-2

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