Cargando…

Directed evolution and targeted mutagenesis to murinize listeria monocytogenes internalin A for enhanced infectivity in the murine oral infection model

BACKGROUND: Internalin A (InlA) is a critical virulence factor which mediates the initiation of Listeria monocytogenes infection by the oral route in permissive hosts. The interaction of InlA with the host cell ligand E-cadherin efficiently stimulates L. monocytogenes entry into human enterocytes, b...

Descripción completa

Detalles Bibliográficos
Autores principales: Monk, Ian R, Casey, Pat G, Hill, Colin, Gahan, Cormac GM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016325/
https://www.ncbi.nlm.nih.gov/pubmed/21144051
http://dx.doi.org/10.1186/1471-2180-10-318