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Pressure Load: The Main Factor for Altered Gene Expression in Right Ventricular Hypertrophy in Chronic Hypoxic Rats

BACKGROUND: The present study investigated whether changes in gene expression in the right ventricle following pulmonary hypertension can be attributed to hypoxia or pressure loading. METHODOLOGY/PRINCIPAL FINDINGS: To distinguish hypoxia from pressure-induced alterations, a group of rats underwent...

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Detalles Bibliográficos
Autores principales: Baandrup, Jonas D., Markvardsen, Lars H., Peters, Christian D., Schou, Uffe K., Jensen, Jens L., Magnusson, Nils E., Ørntoft, Torben F., Kruhøffer, Mogens, Simonsen, Ulf
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016335/
https://www.ncbi.nlm.nih.gov/pubmed/21246034
http://dx.doi.org/10.1371/journal.pone.0015859