Applying an Empirical Hydropathic Forcefield in Refinement May Improve Low-Resolution Protein X-Ray Crystal Structures

BACKGROUND: The quality of X-ray crystallographic models for biomacromolecules refined from data obtained at high-resolution is assured by the data itself. However, at low-resolution, >3.0 Å, additional information is supplied by a forcefield coupled with an associated refinement protocol. These...

Descripción completa

Detalles Bibliográficos
Autores principales: Koparde, Vishal N., Scarsdale, J. Neel, Kellogg, Glen E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016398/
https://www.ncbi.nlm.nih.gov/pubmed/21246043
http://dx.doi.org/10.1371/journal.pone.0015920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016398/
https://www.ncbi.nlm.nih.gov/pubmed/21246043
http://dx.doi.org/10.1371/journal.pone.0015920

Ejemplares similares