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Long-Distance Effects of Insertional Mutagenesis

BACKGROUND: Most common systems of genetic engineering of mammalian cells are associated with insertional mutagenesis of the modified cells. Insertional mutagenesis is also a popular approach to generate random alterations for gene discovery projects. A better understanding of the interaction of the...

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Detalles Bibliográficos
Autores principales: Singhal, Ruchi, Deng, Xiaotao, Chenchik, Alex A., Kandel, Eugene S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016401/
https://www.ncbi.nlm.nih.gov/pubmed/21246045
http://dx.doi.org/10.1371/journal.pone.0015832