Adult Raphe-Specific Deletion of Lmx1b Leads to Central Serotonin Deficiency

The transcription factor Lmx1b is essential for the differentiation and survival of central serotonergic (5-HTergic) neurons during embryonic development. However, the role of Lmx1b in adult 5-HTergic neurons is unknown. We used an inducible Cre-LoxP system to selectively inactivate Lmx1b expression...

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Detalles Bibliográficos
Autores principales: Song, Ning-Ning, Xiu, Jian-Bo, Huang, Ying, Chen, Jia-Yin, Zhang, Lei, Gutknecht, Lise, Lesch, Klaus Peter, Li, He, Ding, Yu-Qiang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016403/
https://www.ncbi.nlm.nih.gov/pubmed/21246047
http://dx.doi.org/10.1371/journal.pone.0015998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016403/
https://www.ncbi.nlm.nih.gov/pubmed/21246047
http://dx.doi.org/10.1371/journal.pone.0015998

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