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PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling

BACKGROUND: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified over the years, it is not always clear which functions or interactions are operative in a particular tumor. This is confou...

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Detalles Bibliográficos
Autores principales: Bebek, Gurkan, Patel, Vishal, Chance, Mark R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016410/
https://www.ncbi.nlm.nih.gov/pubmed/21144021
http://dx.doi.org/10.1186/1471-2105-11-596