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Histone deacetylase regulates high mobility group A2-targeting microRNAs in human cord blood-derived multipotent stem cell aging

Cellular senescence involves a reduction in adult stem cell self-renewal, and epigenetic regulation of gene expression is one of the main underlying mechanisms. Here, we observed that the cellular senescence of human umbilical cord blood-derived multipotent stem cells (hUCB-MSCs) caused by inhibitio...

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Detalles Bibliográficos
Autores principales: Lee, Seunghee, Jung, Ji-Won, Park, Sang-Bum, Roh, Kyounghwan, Lee, Su Yeon, Kim, Ju Han, Kang, Soo-Kyung, Kang, Kyung-Sun
Formato: Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016490/
https://www.ncbi.nlm.nih.gov/pubmed/20652617
http://dx.doi.org/10.1007/s00018-010-0457-9