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Long-Term Blocking of Calcium Channels in mdx Mice Results in Differential Effects on Heart and Skeletal Muscle

The disease mechanisms underlying dystrophin-deficient muscular dystrophy are complex, involving not only muscle membrane fragility, but also dysregulated calcium homeostasis. Specifically, it has been proposed that calcium channels directly initiate a cascade of pathological events by allowing calc...

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Detalles Bibliográficos
Autores principales: Jørgensen, Louise H., Blain, Alison, Greally, Elizabeth, Laval, Steve H., Blamire, Andrew M., Davison, Benjamin J., Brinkmeier, Heinrich, MacGowan, Guy A., Schrøder, Henrik D., Bushby, Kate, Straub, Volker, Lochmüller, Hanns
Formato: Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016598/
https://www.ncbi.nlm.nih.gov/pubmed/21224064
http://dx.doi.org/10.1016/j.ajpath.2010.11.027