Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia

Spinocerebellar ataxias 6 and 7 (SCA6 and SCA7) are neurodegenerative disorders caused by expansion of CAG repeats encoding polyglutamine (polyQ) tracts in CACNA1A, the alpha1A subunit of the P/Q-type calcium channel, and ataxin-7 (ATXN7), a component of a chromatin-remodeling complex, respectively....

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Detalles Bibliográficos
Autores principales: Kahle, Juliette J., Gulbahce, Natali, Shaw, Chad A., Lim, Janghoo, Hill, David E., Barabási, Albert-László, Zoghbi, Huda Y.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016911/
https://www.ncbi.nlm.nih.gov/pubmed/21078624
http://dx.doi.org/10.1093/hmg/ddq496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016911/
https://www.ncbi.nlm.nih.gov/pubmed/21078624
http://dx.doi.org/10.1093/hmg/ddq496

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