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TRAF2 phosphorylation promotes NF-κB–dependent gene expression and inhibits oxidative stress-induced cell death

Tumor necrosis factor α (TNF-α) receptor–associated factor 2 (TRAF2) regulates activation of the c-Jun N-terminal kinase (JNK)/c-Jun and the inhibitor of κB kinase (IKK)/nuclear factor κB (NF-κB) signaling cascades in response to TNF-α stimulation. Gene knockout studies have revealed that TRAF2 inhi...

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Detalles Bibliográficos
Autores principales: Zhang, Laiqun, Blackwell, Ken, Altaeva, Aliya, Shi, Zhaohui, Habelhah, Hasem
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016971/
https://www.ncbi.nlm.nih.gov/pubmed/21119000
http://dx.doi.org/10.1091/mbc.E10-06-0556