The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase

The Wee1 kinase restrains entry into mitosis by phosphorylating and inhibiting cyclin-dependent kinase 1 (Cdk1). The Cdc25 phosphatase promotes entry into mitosis by removing Cdk1 inhibitory phosphorylation. Experiments in diverse systems have established that Wee1 and Cdc25 are regulated by protein...

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Detalles Bibliográficos
Autores principales: Wicky, Sidonie, Tjandra, Hendri, Schieltz, David, Yates, John, Kellogg, Douglas R.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016974/
https://www.ncbi.nlm.nih.gov/pubmed/21119008
http://dx.doi.org/10.1091/mbc.E10-06-0487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016974/
https://www.ncbi.nlm.nih.gov/pubmed/21119008
http://dx.doi.org/10.1091/mbc.E10-06-0487

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