Cargando…
α-synuclein induced synapse damage is enhanced by amyloid-β(1-42)
BACKGROUND: The pathogenesis of Parkinson's disease (PD) and dementia with Lewy bodies (DLB) is associated with the accumulation of aggregated forms of the α-synuclein (αSN) protein. An early event in the neuropathology of PD and DLB is the loss of synapses and a corresponding reduction in the...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017026/ https://www.ncbi.nlm.nih.gov/pubmed/21138585 http://dx.doi.org/10.1186/1750-1326-5-55 |