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α-synuclein induced synapse damage is enhanced by amyloid-β(1-42)
BACKGROUND: The pathogenesis of Parkinson's disease (PD) and dementia with Lewy bodies (DLB) is associated with the accumulation of aggregated forms of the α-synuclein (αSN) protein. An early event in the neuropathology of PD and DLB is the loss of synapses and a corresponding reduction in the...
Autores principales: | Bate, Clive, Gentleman, Steve, Williams, Alun |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017026/ https://www.ncbi.nlm.nih.gov/pubmed/21138585 http://dx.doi.org/10.1186/1750-1326-5-55 |
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