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Tetherin restricts direct cell-to-cell infection of HIV-1

BACKGROUND: Tetherin (BST-2/CD317/HM1.24) is an interferon (IFN)-inducible factor of the innate immune system, recently shown to exert antiviral activity against HIV-1 and other enveloped viruses by tethering nascent viral particles to the cell surface, thereby inhibiting viral release. In HIV-1 inf...

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Detalles Bibliográficos
Autores principales: Kuhl, Björn D, Sloan, Richard D, Donahue, Daniel A, Bar-Magen, Tamara, Liang, Chen, Wainberg, Mark A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017029/
https://www.ncbi.nlm.nih.gov/pubmed/21184674
http://dx.doi.org/10.1186/1742-4690-7-115