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ASIC3 Channels Integrate Agmatine and Multiple Inflammatory Signals through the Nonproton Ligand Sensing Domain

BACKGROUND: Acid-sensing ion channels (ASICs) have long been known to sense extracellular protons and contribute to sensory perception. Peripheral ASIC3 channels represent natural sensors of acidic and inflammatory pain. We recently reported the use of a synthetic compound, 2-guanidine-4-methylquina...

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Detalles Bibliográficos
Autores principales: Li, Wei-Guang, Yu, Ye, Zhang, Zhu-Dan, Cao, Hui, Xu, Tian-Le
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017031/
https://www.ncbi.nlm.nih.gov/pubmed/21143836
http://dx.doi.org/10.1186/1744-8069-6-88