A Novel Strategy for Inducing Enhanced Mucosal HIV-1 Antibody Responses in an Anti-Inflammatory Environment

Prophylactic vaccination against HIV-1 sexual transmission will probably require antibody elicitation at genital mucosal surfaces. However, HIV-1 envelope glycoprotein (Env)-based antigens are weakly immunogenic, particularly when applied mucosally. The polyanion PRO 2000 is safe for human vaginal a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wegmann, Frank, Krashias, George, Lühn, Kerstin, Laamanen, Karoliina, Vieira, Sueli, Jeffs, Simon A., Shattock, Robin J., Sattentau, Quentin J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017049/
https://www.ncbi.nlm.nih.gov/pubmed/21253014
http://dx.doi.org/10.1371/journal.pone.0015861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017049/
https://www.ncbi.nlm.nih.gov/pubmed/21253014
http://dx.doi.org/10.1371/journal.pone.0015861

Ejemplares similares