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A Novel Peptide Derived from Human Apolipoprotein E Is an Inhibitor of Tumor Growth and Ocular Angiogenesis

Angiogenesis is a hallmark of tumor development and metastasis and now a validated target for cancer treatment. We previously reported that a novel dimer peptide (apoEdp) derived from the receptor binding region of human apolipoprotein E (apoE) inhibits virus-induced angiogenesis. However, its role...

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Detalles Bibliográficos
Autores principales: Bhattacharjee, Partha S., Huq, Tashfin S., Mandal, Tarun K., Graves, Richard A., Muniruzzaman, Syed, Clement, Christian, McFerrin, Harris E., Hill, James M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017052/
https://www.ncbi.nlm.nih.gov/pubmed/21253017
http://dx.doi.org/10.1371/journal.pone.0015905