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A Novel Role for Niemann-Pick Disease Type 2C Protein in Papillae Formation

BACKGROUND: Despite the presence of papillary structures and papillary tumors in humans, the mechanism of papillae formation is unknown. We describe herein a novel role for Niemann-Pick disease type 2C (NPC2) protein, a cholesterol binding protein in the lysosome, in papillae formation. METHODOLOGY/...

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Detalles Bibliográficos
Autores principales: Sugawara, Masahiro, Ohye, Hidemi, Tomoda, Chisato, Kogai, Takahiko, Kamata, Yoshimasa, Pezeshkpour, Gholam H., Moatamed, Farhad
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017059/
https://www.ncbi.nlm.nih.gov/pubmed/21253586
http://dx.doi.org/10.1371/journal.pone.0015777