Effective Caspase Inhibition Blocks Neutrophil Apoptosis and Reveals Mcl-1 as Both a Regulator and a Target of Neutrophil Caspase Activation

Human tissue inflammation is terminated, at least in part, by the death of inflammatory neutrophils by apoptosis. The regulation of this process is therefore key to understanding and manipulating inflammation resolution. Previous data have suggested that the short-lived pro-survival Bcl-2 family pro...

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Detalles Bibliográficos
Autores principales: Wardle, David J., Burgon, Joseph, Sabroe, Ian, Bingle, Colin D., Whyte, Moira K. B., Renshaw, Stephen A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017075/
https://www.ncbi.nlm.nih.gov/pubmed/21253591
http://dx.doi.org/10.1371/journal.pone.0015768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017075/
https://www.ncbi.nlm.nih.gov/pubmed/21253591
http://dx.doi.org/10.1371/journal.pone.0015768

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