Elimination of Hepatitis C Virus from Hepatocytes by a Selective Activation of Therapeutic Molecules

To eliminate hepatitis C virus (HCV) from infected hepatocytes, we generated two therapeutic molecules specifically activated in cells infected with HCV. A dominant active mutant of interferon (IFN) regulatory factor 7 (IRF7) and a negative regulator of HCV replication, VAP-C (Vesicle-associated mem...

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Detalles Bibliográficos
Autores principales: Wen, Xiaoyu, Abe, Takayuki, Kukihara, Hiroshi, Taguwa, Shuhei, Mori, Yoshio, Tani, Hideki, Kato, Nobuyuki, Suzuki, Tetsuro, Tatsumi, Masashi, Moriishi, Kohji, Matsuura, Yoshiharu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017098/
https://www.ncbi.nlm.nih.gov/pubmed/21253612
http://dx.doi.org/10.1371/journal.pone.0015967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017098/
https://www.ncbi.nlm.nih.gov/pubmed/21253612
http://dx.doi.org/10.1371/journal.pone.0015967

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