Thermodynamic Stability of Histone H3 Is a Necessary but not Sufficient Driving Force for its Evolutionary Conservation

Determining the forces that conserve amino acid positions in proteins across species is a fundamental pursuit of molecular evolution. Evolutionary conservation is driven by either a protein's function or its thermodynamic stability. Highly conserved histone proteins offer a platform to evaluate...

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Detalles Bibliográficos
Autores principales: Ramachandran, Srinivas, Vogel, Lisa, Strahl, Brian D., Dokholyan, Nikolay V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017104/
https://www.ncbi.nlm.nih.gov/pubmed/21253558
http://dx.doi.org/10.1371/journal.pcbi.1001042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017104/
https://www.ncbi.nlm.nih.gov/pubmed/21253558
http://dx.doi.org/10.1371/journal.pcbi.1001042

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