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A Novel Approach to Pharmacodynamic Assessment of Antimicrobial Agents: New Insights to Dosing Regimen Design

Pharmacodynamic modeling has been increasingly used as a decision support tool to guide dosing regimen selection, both in the drug development and clinical settings. Killing by antimicrobial agents has been traditionally classified categorically as concentration-dependent (which would favor less fra...

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Detalles Bibliográficos
Autores principales: Tam, Vincent H., Nikolaou, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017105/
https://www.ncbi.nlm.nih.gov/pubmed/21253559
http://dx.doi.org/10.1371/journal.pcbi.1001043