Decrypting the Sequence of Structural Events during the Gating Transition of Pentameric Ligand-Gated Ion Channels Based on an Interpolated Elastic Network Model

Despite many experimental and computational studies of the gating transition of pentameric ligand-gated ion channels (pLGICs), the structural basis of how ligand binding couples to channel gating remains unknown. By using a newly developed interpolated elastic network model (iENM), we have attempted...

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Detalles Bibliográficos
Autores principales: Zheng, Wenjun, Auerbach, Anthony
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017109/
https://www.ncbi.nlm.nih.gov/pubmed/21253563
http://dx.doi.org/10.1371/journal.pcbi.1001046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017109/
https://www.ncbi.nlm.nih.gov/pubmed/21253563
http://dx.doi.org/10.1371/journal.pcbi.1001046

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