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A Mutation in the Gene Encoding Mitochondrial Mg(2+) Channel MRS2 Results in Demyelination in the Rat
The rat demyelination (dmy) mutation serves as a unique model system to investigate the maintenance of myelin, because it provokes severe myelin breakdown in the central nervous system (CNS) after normal postnatal completion of myelination. Here, we report the molecular characterization of this muta...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017111/ https://www.ncbi.nlm.nih.gov/pubmed/21253565 http://dx.doi.org/10.1371/journal.pgen.1001262 |