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A Mutation in the Gene Encoding Mitochondrial Mg(2+) Channel MRS2 Results in Demyelination in the Rat

The rat demyelination (dmy) mutation serves as a unique model system to investigate the maintenance of myelin, because it provokes severe myelin breakdown in the central nervous system (CNS) after normal postnatal completion of myelination. Here, we report the molecular characterization of this muta...

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Detalles Bibliográficos
Autores principales: Kuramoto, Takashi, Kuwamura, Mitsuru, Tokuda, Satoko, Izawa, Takeshi, Nakane, Yoshifumi, Kitada, Kazuhiro, Akao, Masaharu, Guénet, Jean-Louis, Serikawa, Tadao
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017111/
https://www.ncbi.nlm.nih.gov/pubmed/21253565
http://dx.doi.org/10.1371/journal.pgen.1001262