Cargando…

A Mutation in the Gene Encoding Mitochondrial Mg(2+) Channel MRS2 Results in Demyelination in the Rat

The rat demyelination (dmy) mutation serves as a unique model system to investigate the maintenance of myelin, because it provokes severe myelin breakdown in the central nervous system (CNS) after normal postnatal completion of myelination. Here, we report the molecular characterization of this muta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuramoto, Takashi, Kuwamura, Mitsuru, Tokuda, Satoko, Izawa, Takeshi, Nakane, Yoshifumi, Kitada, Kazuhiro, Akao, Masaharu, Guénet, Jean-Louis, Serikawa, Tadao
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017111/ https://www.ncbi.nlm.nih.gov/pubmed/21253565 http://dx.doi.org/10.1371/journal.pgen.1001262

Ejemplares similares

The rat Downunder (Du) coat color mutation is associated with eye anomalies and embryonic lethality and maps to a 3.9-Mb region on chromosome 3
por: Hieu, Hoang Trung, et al.
Publicado: (2022)

PHF24 is expressed in the inhibitory interneurons in rats
por: Numakura, Yuki, et al.
Publicado: (2020)

Infertility Associated with Meiotic Failure in the tremor Rat (tm/tm) is Caused by the Deletion of Spermatogenesis Associated 22
por: Ishishita, Satoshi, et al.
Publicado: (2013)

Slc:Wistar outbred rats show close genetic similarity with F344 inbred rats
por: Nakanishi, Satoshi, et al.
Publicado: (2014)

Immunohistochemical Expressions of Main PGE(2) Biosynthesis-related Enzymes and PGE(2) Receptor in Rat Nephrogenesis
por: Yamamoto, Emi, et al.
Publicado: (2011)

Molecular basis of Mg(2+) permeation through the human mitochondrial Mrs2 channel
por: Li, Ming, et al.
Publicado: (2023)

Rat polyomavirus 2 infection in a colony of X-linked severe combined immunodeficiency rats in Japan
por: TANAKA, Miyuu, et al.
Publicado: (2018)

Pathogenesis of Type 2 Epithelial to Mesenchymal Transition (EMT) in Renal and Hepatic Fibrosis
por: Tennakoon, Anusha H., et al.
Publicado: (2015)

L-arginine-induced pancreatitis aggravated by inhibiting Na(+)/Ca(2+) exchanger 1
por: ONO, Naoshige, et al.
Publicado: (2023)

Mrs2p Forms a High Conductance Mg(2+) Selective Channel in Mitochondria
por: Schindl, Rainer, et al.
Publicado: (2007)

A rat model of hypohidrotic ectodermal dysplasia carries a missense mutation in the Edaradd gene
por: Kuramoto, Takashi, et al.
Publicado: (2011)

Relationship of Cell Proliferating Marker Expressions with PGE(2) Receptors in Regenerating Rat Renal Tubules after Cisplatin Injection
por: Yamamoto, Emi, et al.
Publicado: (2010)

Macrophage pathology in hepatotoxicity
por: Yamate, Jyoji, et al.
Publicado: (2022)

Conditional knockdown of hMRS2 results in loss of mitochondrial Mg (+) uptake and cell death
por: Piskacek, Martin, et al.
Publicado: (2009)

Immunophenotypical Characterization of M1/M2 Macrophages and Lymphocytes in Cisplatin-Induced Rat Progressive Renal Fibrosis
por: Nakagawa, Minto, et al.
Publicado: (2021)

Limiting Mrs2-dependent mitochondrial Mg(2+) uptake induces metabolic programming in prolonged dietary stress
por: Madaris, Travis R., et al.
Publicado: (2023)

Origins of Albino and Hooded Rats: Implications from Molecular Genetic Analysis across Modern Laboratory Rat Strains
por: Kuramoto, Takashi, et al.
Publicado: (2012)

Advances on genetic rat models of epilepsy
por: Serikawa, Tadao, et al.
Publicado: (2014)

Comparative Gene Expression Analysis in the Skeletal Muscles of Dysferlin-deficient SJL/J and A/J Mice
por: Kobayashi, Kinji, et al.
Publicado: (2011)

Thy-1 Expressing Mesenchymal Cells in Rat Nephrogenesis in Correlation with Cells Immunoreactive for α-Smooth Muscle Actin and Vimentin
por: Yuasa, Takahiro, et al.
Publicado: (2010)

Dysferlin and Animal Models for Dysferlinopathy
por: Kobayashi, Kinji, et al.
Publicado: (2012)

Spontaneous nephroblastoma with striated muscle differentiation in an F344 rat
por: Tanaka, Natsuki, et al.
Publicado: (2017)

Involvement of neutrophils in rat livers by low-dose thioacetamide administration
por: KURAMOCHI, Mizuki, et al.
Publicado: (2021)

Analyses of damage-associated molecular patterns, particularly biglycan, in cisplatin-induced rat progressive renal fibrosis
por: Nakagawa, Minto, et al.
Publicado: (2023)

Interleukin-19 Gene-Deficient Mice Promote Liver Fibrosis via Enhanced TGF-β Signaling, and the Interleukin-19-CCL2 Axis Is Important in the Direction of Liver Fibrosis
por: Ono, Naoshige, et al.
Publicado: (2023)

Acetaminophen-Induced Rat Hepatotoxicity Based on M1/M2-Macrophage Polarization, in Possible Relation to Damage-Associated Molecular Patterns and Autophagy
por: Tsuji, Yuka, et al.
Publicado: (2020)

A Missense Mutation of the Gene Encoding Synaptic Vesicle Glycoprotein 2A (SV2A) Confers Seizure Susceptibility by Disrupting Amygdalar Synaptic GABA Release
por: Tokudome, Kentaro, et al.
Publicado: (2016)

Generation of Knockout Rats with X-Linked Severe Combined Immunodeficiency (X-SCID) Using Zinc-Finger Nucleases
por: Mashimo, Tomoji, et al.
Publicado: (2010)

Morphological Features of Adult Rats of IS/Kyo and IS-Tlk/Kyo Strains with Lumbar and Caudal Vertebral Anomalies
por: Takano, Masao, et al.
Publicado: (2014)

Use of a chemically induced-colon carcinogenesis-prone Apc-mutant rat in a chemotherapeutic bioassay
por: Yoshimi, Kazuto, et al.
Publicado: (2012)

A rat genetic linkage map and comparative maps for mouse or human homologous rat genes
por: Yamada, J., et al.
Publicado: (1994)

Calponin Expression in Renal Tubulointerstitial Fibrosis Induced in Rats by Cisplatin
por: Yuasa, Takahiro, et al.
Publicado: (2014)

Enhanced Expression of Trib3 during the Development of Myelin Breakdown in dmy Myelin Mutant Rats
por: Shimotsuma, Yukako, et al.
Publicado: (2016)

Unilateral luteoma of the ovary in a pregnant Risso’s dolphin (Grampus griseus)
por: NISHINA, Hironobu, et al.
Publicado: (2017)

Gene expression profile in retinal excitotoxicity induced by L-glutamate in neonatal rats
por: Mitori, Hikaru, et al.
Publicado: (2018)

Effects of dexamethasone on hepatic macrophages in normal livers and thioacetamide-induced acute liver lesions in rats
por: Hada, Noa, et al.
Publicado: (2020)

Progressive Purkinje Cell Degeneration in tambaleante Mutant Mice Is a Consequence of a Missense Mutation in HERC1 E3 Ubiquitin Ligase
por: Mashimo, Tomoji, et al.
Publicado: (2009)

Mrs Arley, a man and Mrs Bjerga
por: Unknown
Publicado: (2002)

Immunolocalization of β-catenin, E-cadherin and N-cadherin in neonate and adult rat kidney
por: TERADA, Naomi, et al.
Publicado: (2017)

Immunohistochemical analyses of the kinetics and distribution of macrophages in the developing rat kidney
por: Matsuyama, Satoshi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_hesei7puckh1l0bi7grejkavuf