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H3K9me-Independent Gene Silencing in Fission Yeast Heterochromatin by Clr5 and Histone Deacetylases

Nucleosomes in heterochromatic regions bear histone modifications that distinguish them from euchromatic nucleosomes. Among those, histone H3 lysine 9 methylation (H3K9me) and hypoacetylation have been evolutionarily conserved and are found in both multicellular eukaryotes and single-cell model orga...

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Detalles Bibliográficos
Autores principales: Hansen, Klavs R., Hazan, Idit, Shanker, Sreenath, Watt, Stephen, Verhein-Hansen, Janne, Bähler, Jürg, Martienssen, Robert A., Partridge, Janet F., Cohen, Amikam, Thon, Geneviève
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017117/
https://www.ncbi.nlm.nih.gov/pubmed/21253571
http://dx.doi.org/10.1371/journal.pgen.1001268