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The autoimmunity of primary biliary cirrhosis and the clonal selection theory

Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease in which an immune-mediated injury targets the small intrahepatic bile ducts. PBC is further characterized by highly specific serum antimitochondrial autoantibodies (AMA) and autoreactive T cells, a striking female predominance,...

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Detalles Bibliográficos
Autores principales: Selmi, Carlo, Mackay, Ian R., Gershwin, M. Eric
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017230/
https://www.ncbi.nlm.nih.gov/pubmed/20975735
http://dx.doi.org/10.1038/icb.2010.126