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The autoimmunity of primary biliary cirrhosis and the clonal selection theory
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease in which an immune-mediated injury targets the small intrahepatic bile ducts. PBC is further characterized by highly specific serum antimitochondrial autoantibodies (AMA) and autoreactive T cells, a striking female predominance,...
Autores principales: | Selmi, Carlo, Mackay, Ian R., Gershwin, M. Eric |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017230/ https://www.ncbi.nlm.nih.gov/pubmed/20975735 http://dx.doi.org/10.1038/icb.2010.126 |
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