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The role of lipid peroxidation products and oxidative stress in activation of the canonical wingless-type MMTV integration site (WNT) pathway in a rat model of diabetic retinopathy

AIMS/HYPOTHESIS: Our recent studies suggest that activation of the wingless-type MMTV integration site (WNT) pathway plays pathogenic roles in diabetic retinopathy and age-related macular degeneration. Here we investigated the causative role of oxidative stress in retinal WNT pathway activation in a...

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Detalles Bibliográficos
Autores principales: Zhou, T., Zhou, K. K., Lee, K., Gao, G., Lyons, T. J., Kowluru, R., Ma, J-x.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017315/
https://www.ncbi.nlm.nih.gov/pubmed/20978740
http://dx.doi.org/10.1007/s00125-010-1943-1