Cargando…
The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes
AIMS/HYPOTHESIS: Sugar has been suggested to promote obesity, diabetes and coronary heart disease (CHD), yet fruit, despite containing sugars, may also have a low glycaemic index (GI) and all fruits are generally recommended for good health. We therefore assessed the effect of fruit with special emp...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017317/ https://www.ncbi.nlm.nih.gov/pubmed/20978741 http://dx.doi.org/10.1007/s00125-010-1927-1 |
_version_ | 1782195897082314752 |
---|---|
author | Jenkins, D. J. A. Srichaikul, K. Kendall, C. W. C. Sievenpiper, J. L. Abdulnour, S. Mirrahimi, A. Meneses, C. Nishi, S. He, X. Lee, S. So, Y. T. Esfahani, A. Mitchell, S. Parker, T. L. Vidgen, E. Josse, R. G. Leiter, L. A. |
author_facet | Jenkins, D. J. A. Srichaikul, K. Kendall, C. W. C. Sievenpiper, J. L. Abdulnour, S. Mirrahimi, A. Meneses, C. Nishi, S. He, X. Lee, S. So, Y. T. Esfahani, A. Mitchell, S. Parker, T. L. Vidgen, E. Josse, R. G. Leiter, L. A. |
author_sort | Jenkins, D. J. A. |
collection | PubMed |
description | AIMS/HYPOTHESIS: Sugar has been suggested to promote obesity, diabetes and coronary heart disease (CHD), yet fruit, despite containing sugars, may also have a low glycaemic index (GI) and all fruits are generally recommended for good health. We therefore assessed the effect of fruit with special emphasis on low GI fruit intake in type 2 diabetes. METHODS: This secondary analysis involved 152 type 2 diabetic participants treated with glucose-lowering agents who completed either 6 months of high fibre or low GI dietary advice, including fruit advice, in a parallel design. RESULTS: Change in low GI fruit intake ranged from −3.1 to 2.7 servings/day. The increase in low GI fruit intake significantly predicted reductions in HbA(1c) (r = −0.206, p = 0.011), systolic blood pressure (r = −0.183, p = 0.024) and CHD risk (r = −0.213, p = 0.008). Change in total fruit intake ranged from −3.7 to 3.2 servings/day and was not related to study outcomes. In a regression analysis including the eight major carbohydrate foods or classes of foods emphasised in the low GI diet, only low GI fruit and bread contributed independently and significantly to predicting change in HbA(1c). Furthermore, comparing the highest with the lowest quartile of low GI fruit intake, the percentage change in HbA(1c) was reduced by −0.5% HbA(1c) units (95% CI 0.2–0.8 HbA(1c) units, p < 0.001). CONCLUSIONS/INTERPRETATION: Low GI fruit consumption as part of a low GI diet was associated with lower HbA(1c), blood pressure and CHD risk and supports a role for low GI fruit consumption in the management of type 2 diabetes. TRIAL REGISTRATION: ClinicalTrials.gov NCT00438698 FUNDING: The Canadian Institutes of Health Research; Canada Research Chair Endowment of the Federal Government of Canada, Loblaw Companies, and Barilla (Italy). ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00125-010-1927-1) contains supplementary material, which is available to authorised users. |
format | Text |
id | pubmed-3017317 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-30173172011-02-04 The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes Jenkins, D. J. A. Srichaikul, K. Kendall, C. W. C. Sievenpiper, J. L. Abdulnour, S. Mirrahimi, A. Meneses, C. Nishi, S. He, X. Lee, S. So, Y. T. Esfahani, A. Mitchell, S. Parker, T. L. Vidgen, E. Josse, R. G. Leiter, L. A. Diabetologia Article AIMS/HYPOTHESIS: Sugar has been suggested to promote obesity, diabetes and coronary heart disease (CHD), yet fruit, despite containing sugars, may also have a low glycaemic index (GI) and all fruits are generally recommended for good health. We therefore assessed the effect of fruit with special emphasis on low GI fruit intake in type 2 diabetes. METHODS: This secondary analysis involved 152 type 2 diabetic participants treated with glucose-lowering agents who completed either 6 months of high fibre or low GI dietary advice, including fruit advice, in a parallel design. RESULTS: Change in low GI fruit intake ranged from −3.1 to 2.7 servings/day. The increase in low GI fruit intake significantly predicted reductions in HbA(1c) (r = −0.206, p = 0.011), systolic blood pressure (r = −0.183, p = 0.024) and CHD risk (r = −0.213, p = 0.008). Change in total fruit intake ranged from −3.7 to 3.2 servings/day and was not related to study outcomes. In a regression analysis including the eight major carbohydrate foods or classes of foods emphasised in the low GI diet, only low GI fruit and bread contributed independently and significantly to predicting change in HbA(1c). Furthermore, comparing the highest with the lowest quartile of low GI fruit intake, the percentage change in HbA(1c) was reduced by −0.5% HbA(1c) units (95% CI 0.2–0.8 HbA(1c) units, p < 0.001). CONCLUSIONS/INTERPRETATION: Low GI fruit consumption as part of a low GI diet was associated with lower HbA(1c), blood pressure and CHD risk and supports a role for low GI fruit consumption in the management of type 2 diabetes. TRIAL REGISTRATION: ClinicalTrials.gov NCT00438698 FUNDING: The Canadian Institutes of Health Research; Canada Research Chair Endowment of the Federal Government of Canada, Loblaw Companies, and Barilla (Italy). ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00125-010-1927-1) contains supplementary material, which is available to authorised users. Springer-Verlag 2010-10-27 2011 /pmc/articles/PMC3017317/ /pubmed/20978741 http://dx.doi.org/10.1007/s00125-010-1927-1 Text en © The Author(s) 2010 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. |
spellingShingle | Article Jenkins, D. J. A. Srichaikul, K. Kendall, C. W. C. Sievenpiper, J. L. Abdulnour, S. Mirrahimi, A. Meneses, C. Nishi, S. He, X. Lee, S. So, Y. T. Esfahani, A. Mitchell, S. Parker, T. L. Vidgen, E. Josse, R. G. Leiter, L. A. The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes |
title | The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes |
title_full | The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes |
title_fullStr | The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes |
title_full_unstemmed | The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes |
title_short | The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes |
title_sort | relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017317/ https://www.ncbi.nlm.nih.gov/pubmed/20978741 http://dx.doi.org/10.1007/s00125-010-1927-1 |
work_keys_str_mv | AT jenkinsdja therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT srichaikulk therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT kendallcwc therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT sievenpiperjl therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT abdulnours therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT mirrahimia therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT menesesc therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT nishis therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT hex therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT lees therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT soyt therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT esfahania therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT mitchells therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT parkertl therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT vidgene therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT josserg therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT leiterla therelationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT jenkinsdja relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT srichaikulk relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT kendallcwc relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT sievenpiperjl relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT abdulnours relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT mirrahimia relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT menesesc relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT nishis relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT hex relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT lees relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT soyt relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT esfahania relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT mitchells relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT parkertl relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT vidgene relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT josserg relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes AT leiterla relationoflowglycaemicindexfruitconsumptiontoglycaemiccontrolandriskfactorsforcoronaryheartdiseaseintype2diabetes |