Active Adenoviral Vascular Penetration by Targeted Formation of Heterocellular Endothelial–epithelial Syncytia

The endothelium imposes a structural barrier to the extravasation of systemically delivered oncolytic adenovirus (Ad). Here, we introduced a transendothelial route of delivery in order to increase tumor accumulation of virus particles (vp) beyond that resulting from convection-dependent extravasatio...

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Detalles Bibliográficos
Autores principales: Chen, Hannah H, Cawood, Ryan, El-Sherbini, Yasser, Purdie, Laura, Bazan-Peregrino, Miriam, Seymour, Leonard W, Carlisle, Robert C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017442/
https://www.ncbi.nlm.nih.gov/pubmed/20877345
http://dx.doi.org/10.1038/mt.2010.209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017442/
https://www.ncbi.nlm.nih.gov/pubmed/20877345
http://dx.doi.org/10.1038/mt.2010.209

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