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PK20, a new opioid-neurotensin hybrid peptide that exhibits central and peripheral antinociceptive effects

BACKGROUND: The clinical treatment of various types of pain relies upon the use of opioid analgesics. However most of them produce, in addition to the analgesic effect, several side effects such as the development of dependence and addiction as well as sedation, dysphoria, and constipation. One solu...

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Detalles Bibliográficos
Autores principales: Kleczkowska, Patrycja, Kosson, Piotr, Ballet, Steven, Van den Eynde, Isabelle, Tsuda, Yuko, Tourwé, Dirk, Lipkowski, Andrzej W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017538/
https://www.ncbi.nlm.nih.gov/pubmed/21134256
http://dx.doi.org/10.1186/1744-8069-6-86