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PK20, a new opioid-neurotensin hybrid peptide that exhibits central and peripheral antinociceptive effects
BACKGROUND: The clinical treatment of various types of pain relies upon the use of opioid analgesics. However most of them produce, in addition to the analgesic effect, several side effects such as the development of dependence and addiction as well as sedation, dysphoria, and constipation. One solu...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017538/ https://www.ncbi.nlm.nih.gov/pubmed/21134256 http://dx.doi.org/10.1186/1744-8069-6-86 |