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Dendritic Cells Transfected with scFv from Mab 7.B12 Mimicking Original Antigen gp43 Induces Protection against Experimental Paracoccidioidomycosis

Paracoccidioidomycosis (PCM), endemic in Latin America, is a progressive systemic mycosis caused by Paracoccidioides brasiliensis (P. brasiliensis), which primarily attacks lung tissue. Dendritic cells (DCs) are able to initiate a response in naïve T cells, and they also participate in Th-cell educa...

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Detalles Bibliográficos
Autores principales: Ferreira, Karen S., Maranhão, Andrea Q., Garcia, Maria C. C., Brígido, Marcelo M., Santos, Suelen S., Lopes, José D., Almeida, Sandro R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017565/
https://www.ncbi.nlm.nih.gov/pubmed/21249212
http://dx.doi.org/10.1371/journal.pone.0015935