TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

DNA double-strand breaks enhance homologous recombination in cells and have been exploited for targeted genome editing through use of engineered endonucleases. Here we report the creation and initial characterization of a group of rare-cutting, site-specific DNA nucleases produced by fusion of the r...

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Detalles Bibliográficos
Autores principales: Li, Ting, Huang, Sheng, Jiang, Wen Zhi, Wright, David, Spalding, Martin H., Weeks, Donald P., Yang, Bing
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017587/
https://www.ncbi.nlm.nih.gov/pubmed/20699274
http://dx.doi.org/10.1093/nar/gkq704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017587/
https://www.ncbi.nlm.nih.gov/pubmed/20699274
http://dx.doi.org/10.1093/nar/gkq704

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