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Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat protein

The pharmacological disruption of the interaction between the HIV Tat protein and its cognate transactivation response RNA (TAR) would generate novel anti-viral drugs with a low susceptibility to drug resistance, but efforts to discover ligands with sufficient potency to warrant pharmaceutical devel...

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Detalles Bibliográficos
Autores principales: Davidson, Amy, Patora-Komisarska, Krystyna, Robinson, John A., Varani, Gabriele
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017588/
https://www.ncbi.nlm.nih.gov/pubmed/20724442
http://dx.doi.org/10.1093/nar/gkq713