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Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat protein
The pharmacological disruption of the interaction between the HIV Tat protein and its cognate transactivation response RNA (TAR) would generate novel anti-viral drugs with a low susceptibility to drug resistance, but efforts to discover ligands with sufficient potency to warrant pharmaceutical devel...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017588/ https://www.ncbi.nlm.nih.gov/pubmed/20724442 http://dx.doi.org/10.1093/nar/gkq713 |