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Structural basis of microRNA length variety

The biogenesis of human microRNAs (miRNAs) includes two RNA cleavage steps in which the activities of the RNases Drosha and Dicer are involved. miRNAs of diverse lengths are generated from different genes, and miRNAs that are heterogeneous in length are produced from a single miRNA gene. We determin...

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Detalles Bibliográficos
Autores principales: Starega-Roslan, Julia, Krol, Jacek, Koscianska, Edyta, Kozlowski, Piotr, Szlachcic, Wojciech J., Sobczak, Krzysztof, Krzyzosiak, Wlodzimierz J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017592/
https://www.ncbi.nlm.nih.gov/pubmed/20739353
http://dx.doi.org/10.1093/nar/gkq727