Ice-COLD-PCR enables rapid amplification and robust enrichment for low-abundance unknown DNA mutations

Identifying low-abundance mutations within wild-type DNA is important in several fields of medicine, including cancer, prenatal diagnosis and infectious diseases. However, utilizing the clinical and diagnostic potential of rare mutations is limited by sensitivity of the molecular techniques employed...

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Detalles Bibliográficos
Autores principales: Milbury, Coren A., Li, Jin, Makrigiorgos, G. Mike
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017621/
https://www.ncbi.nlm.nih.gov/pubmed/20937629
http://dx.doi.org/10.1093/nar/gkq899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017621/
https://www.ncbi.nlm.nih.gov/pubmed/20937629
http://dx.doi.org/10.1093/nar/gkq899

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