Regulation of Mixed Lineage Kinase 3 is Required for Neurofibromatosis-2-Mediated Growth Suppression in Human Cancer

The Neurofibromatosis-2 (NF2) tumor suppressor merlin negatively regulates cell proliferation in numerous cell types. We have previously shown that the NF2 protein (merlin/schwannomin) associates with mixed lineage kinase 3 (MLK3), a mitogen-activated protein kinase (MAPK) kinase kinase that is requ...

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Detalles Bibliográficos
Autores principales: Zhan, Yu, Modi, Nidhi, Stewart, Amanda M., Hieronimus, Robert I., Liu, Jinsong, Gutmann, David H., Chadee, Deborah N.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017676/
https://www.ncbi.nlm.nih.gov/pubmed/20890305
http://dx.doi.org/10.1038/onc.2010.453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017676/
https://www.ncbi.nlm.nih.gov/pubmed/20890305
http://dx.doi.org/10.1038/onc.2010.453

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