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Deficiency of insulin-like growth factor 1 reduces vulnerability to chronic alcohol intake-induced cardiomyocyte mechanical dysfunction: role of AMPK

Circulating insulin-like growth factor I (IGF-1) levels are closely associated with cardiac performance although the role of IGF-1 in alcoholic cardiac dysfunction is unknown. This study was designed to evaluate the impact of severe liver IGF-1 deficiency (LID) on chronic alcohol-induced cardiomyocy...

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Detalles Bibliográficos
Autores principales: Ge, Wei, Li, Qun, Turdi, Subat, Wang, Xiao-Ming, Ren, Jun
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017727/
https://www.ncbi.nlm.nih.gov/pubmed/20731752
http://dx.doi.org/10.1111/j.1582-4934.2010.01158.x