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Addressing the Challenge of Defining Valid Proteomic Biomarkers and Classifiers

BACKGROUND: The purpose of this manuscript is to provide, based on an extensive analysis of a proteomic data set, suggestions for proper statistical analysis for the discovery of sets of clinically relevant biomarkers. As tractable example we define the measurable proteomic differences between appar...

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Detalles Bibliográficos
Autores principales: Dakna, Mohammed, Harris, Keith, Kalousis, Alexandros, Carpentier, Sebastien, Kolch, Walter, Schanstra, Joost P, Haubitz, Marion, Vlahou, Antonia, Mischak, Harald, Girolami, Mark
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017845/
https://www.ncbi.nlm.nih.gov/pubmed/21208396
http://dx.doi.org/10.1186/1471-2105-11-594