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In silico reversal of repeat-induced point mutation (RIP) identifies the origins of repeat families and uncovers obscured duplicated genes

BACKGROUND: Repeat-induced point mutation (RIP) is a fungal genome defence mechanism guarding against transposon invasion. RIP mutates the sequence of repeated DNA and over time renders the affected regions unrecognisable by similarity search tools such as BLAST. RESULTS: DeRIP is a new software too...

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Detalles Bibliográficos
Autores principales: Hane, James K, Oliver, Richard P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017866/
https://www.ncbi.nlm.nih.gov/pubmed/21106049
http://dx.doi.org/10.1186/1471-2164-11-655