Cargando…
Mass-transport limitations in spot-based microarrays
Mass transport of analyte to surface-immobilized affinity reagents is the fundamental bottleneck for sensitive detection in solid-support microarrays and biosensors. Analyte depletion in the volume adjacent to the sensor causes deviation from ideal association, significantly slows down reaction kine...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Optical Society of America
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018043/ https://www.ncbi.nlm.nih.gov/pubmed/21258524 http://dx.doi.org/10.1364/BOE.1.000983 |