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Mass-transport limitations in spot-based microarrays

Mass transport of analyte to surface-immobilized affinity reagents is the fundamental bottleneck for sensitive detection in solid-support microarrays and biosensors. Analyte depletion in the volume adjacent to the sensor causes deviation from ideal association, significantly slows down reaction kine...

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Detalles Bibliográficos
Autores principales:	Zhao, Ming, Wang, Xuefeng, Nolte, David
Formato:	Texto
Lenguaje:	English
Publicado:	Optical Society of America 2010
Materias:	Biosensors and Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018043/ https://www.ncbi.nlm.nih.gov/pubmed/21258524 http://dx.doi.org/10.1364/BOE.1.000983

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